A monoclonal antibody which blocks infection with feline immunodeficiency virus identifies a possible non-CD4 receptor.

نویسندگان

  • M J Hosie
  • B J Willett
  • T H Dunsford
  • O Jarrett
  • J C Neil
چکیده

Monoclonal antibody vpg15 detects a 24-kDa cell surface protein on feline cells permissive for infection with feline immunodeficiency virus (FIV). The antibody blocks infection of FIV-susceptible cells, and expression of the vpg15 marker is decreased in FIV-infected cells in vitro. These results suggest that the antibody may recognize an FIV receptor distinct from CD4.

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عنوان ژورنال:
  • Journal of virology

دوره 67 3  شماره 

صفحات  -

تاریخ انتشار 1993